- Case Report
- Neurology
- Type I Chiari malformation presenting orthostatic syncope who treated with decompressive surgery
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Hyun-Seung Shin, Jeong A Kim, Dong-Seok Kim, Joon Soo Lee
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Clin Exp Pediatr. 2016;59(Suppl 1):S149-S151. Published online November 30, 2016
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Chiari malformations are a congenital anomaly of the hindbrain. The most common, Chiari malformation type I (CM-I), is characterized by herniation of the cerebellar tonsils extending at least 3 mm below the plane of the foramen magnum. Consequently, CM-I is associated with hydrocephalus and symptoms involving compression of the cervicomedullary junction by ectopic tonsils. Several studies have reported the clinical... |
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- Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia
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Yun-Jin Lee, Kee-Yang Chung, Hoon-Chul Kang, Heung Dong Kim, Joon Soo Lee
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Clin Exp Pediatr. 2015;58(9):354-357. Published online September 21, 2015
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Parry-Romberg syndrome (PRS) is a rare, acquired disorder characterized by progressive unilateral facial atrophy of the skin, soft tissue, muscles, and underlying bony structures that may be preceded by cutaneous induration. It is sometimes accompanied by ipsilateral brain lesions and neurological symptoms. Here we present the case of a 10-year-old girl with right-sided PRS and recurrent monoplegic ataxia of the... |
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- Original Article
- Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience
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Jungpyo Lee, Hyeeun Kwon, Joon Soo Lee, Heung Dong Kim, Hoon-Chul Kang
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Clin Exp Pediatr. 2015;58(7):251-255. Published online July 22, 2015
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Purpose The widespread introduction of bacterial conjugate vaccines has decreased the risk of cerebrospinal fluid (CSF) pleocytosis due to bacterial meningitis (BM) in children. However, most patients with CSF pleocytosis are hospitalized and treated with parenteral antibiotics for several days. The bacterial meningitis score (BMS) is a validated multivariate model derived from a pediatric population in the postconjugate vaccine era and... |
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- Case Report
- Chronic inflammatory demyelinating polyneuropathy in children: a report of four patients with variable relapsing courses
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Soo Jin Chang, Ji Hyun Lee, Shin Hye Kim, Joon Soo Lee, Heung Dong Kim, Joon Won Kang, Young Mock Lee, Hoon-Chul Kang
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Clin Exp Pediatr. 2015;58(5):194-198. Published online May 22, 2015
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Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronically progressive or relapsing symmetric sensorimotor disorder presumed to occur because of immunologic antibody-mediated reactions. To understand the clinical courses of CIDP, we report variable CIDP courses in children with respect to initial presentation, responsiveness to medical treatment, and recurrence interval. Four patients who were diagnosed with acute-onset and relapsing CIDP courses at... |
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- Original Article
- Screening for depression and anxiety disorder in children with headache
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Sang Mi Lee, Jung-Rim Yoon, Yoon Young Yi, Soyong Eom, Joon Soo Lee, Heung Dong Kim, Keun-Ah Cheon, Hoon-Chul Kang
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Clin Exp Pediatr. 2015;58(2):64-68. Published online February 28, 2015
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Purpose The purpose of this study was to investigate the importance of initial screening tests for depression and anxiety disorders in children with headache. In addition, this study evaluated whether the Children's Depression Inventory (CDI) and Revised Children's Manifest Anxiety Scale (RCMAS) are suitable for screening symptoms of depression and anxiety. MethodsA retrospective chart review was conducted of 720 children aged 7-17... |
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- Case Report
- Congenital muscular dystrophy type 1A with residual merosin expression
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Hyo Jeong Kim, Young-Chul Choi, Hyung Jun Park, Young-Mock Lee, Heung Dong Kim, Joon Soo Lee, Hoon-Chul Kang
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Clin Exp Pediatr. 2014;57(3):149-152. Published online March 31, 2014
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Congenital muscular dystrophy type 1A (MDC1A) is an autosomal recessive disorder characterized by hypotonia, elevated serum creatine kinase level, delayed motor milestones, white matter changes observed by brain magnetic resonance imaging, and normal intelligence. A mutation in the laminin α2 (LAMA2) gene, located at 6q22-23, is a genetic cause of MDC1A. Patients have merosin (laminin α2)-deficient skeletal muscles. However, the... |
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- Wernicke's encephalopathy in a child with high dose thiamine therapy
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So Won Park, Yoon Young Yi, Jung Woo Han, Heung Dong Kim, Joon Soo Lee, Hoon-Chul Kang
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Clin Exp Pediatr. 2014;57(11):496-499. Published online November 30, 2014
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Wernicke's encephalopathy is an acute neurological disorder characterized by mental confusion, oculomotor dysfunction, and ataxia. It has been reported in individuals with alcohol dependence, hyperemesis gravidarum, and prolonged parenteral nutrition without vitamin supplementation. Here we present the case of a 13-year-old male patient with neuroblastoma and a history of poor oral intake and nausea for 3 months. After admission, he... |
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- Review Article
- Temporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes
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Yun-Jin Lee, Joon Soo Lee
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Clin Exp Pediatr. 2013;56(7):275-281. Published online July 19, 2013
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Temporal lobe epilepsy (TLE) is the most common type of medically intractable epilepsy in adults and children, and mesial temporal sclerosis is the most common underlying cause of TLE. Unlike in the case of adults, TLE in infants and young children often has etiologies other than mesial temporal sclerosis, such as tumors, cortical dysplasia, trauma, and vascular malformations. Differences in... |
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- Original Article
- Epilepsy in Korean patients with Angelman syndrome
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Sung-Hee Park, Jung-Rim Yoon, Heung Dong Kim, Joon Soo Lee, Young-Mock Lee, Hoon-Chul Kang
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Clin Exp Pediatr. 2012;55(5):171-176. Published online May 21, 2012
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Purpose The aim of this study was to investigate the natural history of epilepsy and response to anti-epileptic drug treatment in patients with Angelman syndrome (AS) in Korea. MethodsWe retrospectively reviewed the clinical records of 14 patients diagnosed with epilepsy out of a total of 17 patients with a genetic diagnosis of AS. These patients were seen at the Department of Pediatric... |
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- Electrocardiography as an early cardiac screening test in children with mitochondrial disease
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Ran Baik, Jung Hyun Chae, Young Mock Lee, Hoon Chul Kang, Joon Soo Lee, Heung Dong Kim
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Clin Exp Pediatr. 2010;53(5):644-647. Published online May 31, 2010
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Purpose To evaluate myocardial conductivity to understand cardiac involvement in patients with mitochondrial disease. MethodsWe performed retrospective study on fifty-seven nonspecific mitochondrial encephalopathy patients with no clinical cardiac manifestations. The patients were diagnosed with mitochondrial respiratory chain complex defects through biochemical enzyme assays of muscle tissue. We performed standard 12-lead electrocardiography (ECG) on all patients. ResultsECG abnormalities were observed in 30 patients (52.6%).... |
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- Ocular manifestations in Leigh syndrome
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Kyo Ryung Kim, Suk Ho Byeon, Young Mock Lee, Hoon Chul Kang, Joon Soo Lee, Heung Dong Kim
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Clin Exp Pediatr. 2010;53(2):163-166. Published online February 15, 2010
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Purpose : Leigh syndrome is a typical type of mitochondrial disease. This study was conducted to analyze the types of ophthalmologic symptoms and results of funduscopy conducted in the ophthalmologic examination of patients with Leigh syndrome.
Methods : Funduscopy was conducted on 24 subjects, who were chosen among those diagnosed as having mitochondrial respiratory chain complex defect and who were clinically... |
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- Risk factors of ocular involvement in children with mitochondrial respiratory chain complex defect
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Jung Hyun Chae, Jung Hun Lee, Kyo Ryung Kim, Suk Ho Byeon, Young Mock Lee, Hoon Chul Kang, Joon Soo Lee, Heung Dong Kim
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Clin Exp Pediatr. 2010;53(12):994-999. Published online December 31, 2010
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Purpose Mitochondrial dysfunction can present with various symptoms depending on the organ it has affected. This research tried to analyze the ophthalmologic symptoms and ophthalmologic examination (OE) results in patients with mitochondrial disease (MD). MethodsSeventy-four patients diagnosed with mitochondrial respiratory chain complex defect with biochemical enzyme assay were included in the study. They were divided into 2 groups based on the OE... |
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- Case Report
- A case of hippocampal sclerosis diagnosed as cortical
dysplasia due to preoperative brain MRI finding
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Jun Seok Lee, Kyo Ryung Kim, Jeong Tae Kim, Min Jung Choi, Young Mock Lee, Heung Dong Kim, Joon Soo Lee, Dong Seok Kim, Tae Seong Kim
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Clin Exp Pediatr. 2010;53(1):106-110. Published online January 15, 2010
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Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white... |
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- Original Article
- Ictal single-photon emission computed tomography with slow dye
injection for determining primary epileptic foci in infantile spasms
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Yun Jung Hur, Joon Soo Lee, Hoon Chul Kang, Hye Jung Park, Mi Jin Yun, Heung Dong Kim
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Clin Exp Pediatr. 2009;52(7):804-810. Published online July 15, 2009
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Purpose : We investigated whether ictal single-photon emission computed tomography (SPECT) with prolonged injection of technetium-99m (99mTc) ethyl cysteinate dimer during repeated spasms can localize the epileptogenic foci in children with infantile spasms.
Methods : Fourteen children with infantile spasms (11 boys, 3 girls; mean age, 2.2¡¾1.3 years) were examined. When a cluster of spasms was detected during video electroencephalography (EEG)... |
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- Clinical manifestations and neuroimaging findings of schizencephaly in children
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Jae Rang Lee, Seung Kim, Young Mock Lee, Joon Soo Lee, Heung Dong Kim
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Clin Exp Pediatr. 2009;52(4):458-463. Published online April 15, 2009
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Purpose : Schizencephaly is a uncommon congenital brain anomaly characterized by congenital clefts spanning the cerebral hemispheres from pial surface to lateral ventricles and lined by gray matter. In this study, we investigated the clinical manifestation and radiologic findings of pediatric schizencephaly.
Methods : The data of 13 patients who were diagnosed with schizencephaly in Severance Childrens Hospital and Yongdong... |
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- Analysis on the association between EEG and 2-deoxy-2-[18F]-D-glucose (FDG)-PET
findings in children with epilepsy
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Yun Jung Hur, Joon Soo Lee, Jong Doo Lee, Heung Dong Kim
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Clin Exp Pediatr. 2008;51(3):286-292. Published online March 15, 2008
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Purpose : We performed EEG and PET on children with epilepsy concomitantly in order to evaluate the effects of epileptiform and non-epileptiform discharge of EEG on glucose metabolism.
Methods : Seventy three children with epilepsy who had PET and EEG simultaneously were included in our study. The subjects were classified in two ways: (1) based on the frequency of epileptiform... |
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- Case Report
- A Case of Neurofibromatosis Combined with Ectopic Kidney
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Eugene Yang, Bo Hyun Kim, Joon Soo Lee
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Clin Exp Pediatr. 2005;48(4):448-452. Published online April 15, 2005
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Neurofibromatosis(NF) is an autosomal dominant disorder, probably of neural crest origin that affects all three germinal layers. It is a group of heterogeneous multisystemic neurocutaneous disorders involving both neuroectodermal and mesenchymal derivatives. Type 1(von Recklinghausen disease) is the most common neurocutaneous disorder among the eight subtypes. Previous reports showed various involvements in the renal organ. Renovascular hypertension is the most... |
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- Original Article
- Clinical Characteristics of Complex Partial Seizures : a Temporal versus a Frontal Lobe Onset
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Joon Soo Lee, Jae Hyun Park, Chang Jun Coe
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Clin Exp Pediatr. 1998;41(6):769-774. Published online June 15, 1998
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Purpose : This study was performed to correlate clinical behaviours with either a temporal or
frontal site of origin and then to identify behaviours that might have a significant practical value
in differentiating a temporal from a frontal focus and thus reduce the need for invasive
monitoring.
Methods : We analysed 129 seizures that occured during video-EEG monitoring in 13 patients
with temporal lobe epilepsy(TLE)... |
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- Case Report
- One Case of Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome due to Mycoplasma pneumoniae In fection
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Soo Kyung Lee, Joon Soo Lee, Soo Young Lee, Byung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
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Clin Exp Pediatr. 1993;36(10):1441-1446. Published online October 15, 1993
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Bronchiolitis obliterans is an infrequent disorder characterized by partial or complete obstruction of bronchi and bronchioles by fibrous tissue following an insult to the lower respiratory tract. In the pediatric population, Bronchiolitis obliterans has most frequently been preceded by respiratory tract infection by adenovirus, influenza, measles. But it may occur in young adults after mycoplasma infection. We experienced the case... |
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- 2 Cases with Adult Respiratory Distress Syndrome in Infant and Young Child
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Hye Jung Joo, Im Jae Park, Joon Soo Lee, Soo Young Lee, Byeung Ju Jeoung, Kyu Earn Kim, Ki Young Lee, Hyunee Yim, Soon Won Hong, Woo Hee Jung
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Clin Exp Pediatr. 1992;35(8):1118-1126. Published online August 15, 1992
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Adult respiratory distress syndrome has been described as a clinical syndrome of respiratory distress and need for mechanical ventilation with positive end-expiratory pressure, diffuse pulmonary infiltration on thoracic roentgenogram, impaired pulmonary compliance, decreased lung volumes and capacities, increased alveoloarterial oxygen gradient and hyaline membrane formation. It is the clinical manifestation of injury to the terminal alveolocapillary unit as a result... |
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- A Case of Pararenal Pseudocyst and Congenital Hydronephrosis with Pisterior Urethral Valve
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Jeong Lim Kim, Seung Yul Lee, Joon Soo Lee, Ki Soo Pai, Jae Seung Lee, Seung Kang Choi, Jin Suck Suh
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Clin Exp Pediatr. 1992;35(2):263-268. Published online February 15, 1992
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Pararenal pseudocyst is an encapsulated cystic collection of chronically extravasated urine or serous fluid, usually occurring in the perirenal space by renal trauma, operative procedures or obstructive uropathy such as posterior urethral valve, or calculi, tumors of genitourinary tract and often associated with hydronephrosis and displacement of the kidney.
We experienced a case of pararenal pseudocyst, right and congenital hydronephrosis, left... |
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- Original Article
- A case of Wandering spleen.
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Soh Yeon Kim, Joon Soo Lee, Kyu Earn Kim, Seung Kyu Lee, Choon Sik Yoon, Ki Keun Oh, Young Jin Chung
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Clin Exp Pediatr. 1991;34(4):577-581. Published online April 30, 1991
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Wandering spleen is a term applied to the condition in which a long pedicle allows the spleen to lie
in an abnormal location. The condition is usually symptomless but mild discomfort or severe
abdominal pain may occur with torsion of the pedicle and with splenic congestion. There may be a
masss palpable in the pelvic cavity or midabdomen which may be misdiagnosed as... |
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